This document highlights the alarming increase in plastic production and its negative impact on human health and the environment. Plastic pollution is causing lethal effects in various organisms and altering global carbon cycling. Additionally, plastic contributes to climate change, generating significant greenhouse gas emissions. The document emphasizes the need for a shift to a circular economy for plastics to prevent pollution and reduce emissions. It also emphasizes the inclusion of informal waste pickers and the importance of comprehensive and integrated solutions across the life cycle of plastics. Harmonized international measures and legal obligations are crucial for effective action.