The publication focuses on the role of rivers as an ideal opportunity for intercepting plastic pollution before it reaches the ocean. The first section focuses on the state of the science regarding river plastic pollution on a global scale, including causes and estimates of the volume of plastic pollution that enters the ocean from rivers. The publication covers the available technologies and collaborations that can physically intercept plastic pollution in rivers. Finally the report includes recommendations for designing a river plastic pollution intervention strategy, along with a global call to action.